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| Phentermine is the most commonly prescribed prescription appetite suppressant, accounting for 50% of the prescriptions. Part of this reason is because it's significantly cheaper than the other major FDA-approved diet drugs, Meridia and Xenical. Phentermine first received approval from the Food and Drug Administration (FDA) in 1959 as an appetite suppressant for the short-term treatment of obesity. Phentermine resin became available in the United States in 1959 and Phentermine Hydrochloride in the early 1970s. In the US, Phentermine is currently sold under the brand names Ionamin® (Medeva Pharmaceuticals) and Adipex-P® (Gate Pharmaceuticals). It is also available as a generic medication, known as 'phentermine'. Previously, it was sold under the name Fastin® (formerly produced by King Pharmaceuticals for SmithKline Beecham). In December 1998, SK-Beecham withdrew Fastin from the market. As Phentermine is an older drug, no new efficacy trials have been conducted. The one notable exception, are several trials on the combination of Phentermine and Fenfluramine in the early and mid 1990s. |
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